A patient presents with a sudden, severe headache — “the worst headache of my life.” They’re awake, vitals are stable. Do you call it a migraine, give pain meds, and discharge? Not so fast. This could be a subarachnoid hemorrhage (SAH) — a time-critical emergency that rookies often miss.
Why It Matters
- SAH is most often caused by ruptured intracranial aneurysm.
- Mortality: up to 30–40% at 30 days.
- Survivors often left with major neurological deficits.
- Missed SAH = malpractice nightmare — one of the most litigated ED diagnoses.
Classic Presentation
- Thunderclap headache: abrupt onset, maximal intensity within 1 minute.
- Often described as “worst headache ever.”
- May occur during exertion, sexual activity, or Valsalva.
Associated Features
- Nausea, vomiting.
- Photophobia, neck stiffness (meningeal irritation).
- LOC at onset in some cases.
- Focal neuro deficits or seizures in ~25%.
Step 1: Initial ED Assessment
- ABCs: airway protection if decreased GCS.
- Neuro exam: cranial nerves, motor, speech, pupillary reactivity.
- Vital signs: hypertension, bradycardia may indicate rising ICP.
Step 2: Imaging
- Non-contrast CT head is first-line.
- Sensitivity:
- ~98% within first 6 hrs.
- Falls to <85% after 6–12 hrs.
- Sensitivity:
- If CT negative but suspicion high → Lumbar puncture for xanthochromia (bilirubin breakdown).
- CTA head often performed if aneurysm suspected, or as part of CT stroke protocol.
Step 3: Labs
- CBC, renal function, coagulation profile.
- Type & crossmatch (for possible surgery).
Step 4: ED Management
- Blood pressure control: target SBP <140 mmHg (nicardipine, labetalol).
- Pain control & antiemetics: reduces rebleeding risk from surges.
- Nimodipine: 60 mg PO/NG q4h (neuroprotective, prevents vasospasm).
- Seizure management: treat if seizures occur (levetiracetam often used).
- Reverse anticoagulation/antiplatelets if applicable.
- Neurosurgery/neuro ICU consult urgently — definitive management = aneurysm coiling or clipping.
Pitfalls Rookies Make
- Dismissing thunderclap headache as migraine, tension headache, or viral illness.
- Relying on negative CT >6 hrs after onset without LP.
- Forgetting nimodipine — one of the few interventions proven to improve outcomes.
- Treating only the pain without addressing BP control or workup.
- Not consulting neurosurgery early.
Rookie Pearls
- “Worst headache of life” = SAH until proven otherwise.
- CT within 6 hrs is very sensitive, but beyond that you must LP or CTA.
- Even a normal neuro exam does not rule out SAH.
- Always document onset time, risk factors, and your rationale for ruling in/out.
- Involve neurosurgery early — definitive care is procedural, not medical.
Take-Home Message
For rookies:
- SAH = thunderclap headache + high stakes.
- CT first, then LP or CTA if suspicion remains.
- Treat BP, start nimodipine, consult neurosurgery.
- Don’t dismiss patients who look “too well” — many SAH patients walk into the ED.
Remember: Missing SAH is one of the biggest rookie mistakes in emergency medicine — don’t let it be yours.







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